A taxonomic revision of Secamone (Apocynaceae) in the Philippines is presented. Nineteen species are recognized of which eight are described as new: Secamone commutata, S. crenata, S. edanoi, S. fusiformis, S. glandulifera, S. luzonensis, S. mindanaensis and S. pyriformis. Six new combinations are made: Secamone fenixii (Tsiang) Klack., S. glauca (Decne.) Klack., S. lepta (Tsiang) Klack., S. loheri (Schltr.) Klack., S. merrillii (Schltr.) Klack. and S. radiata (Tsiang) Klack. Drawings, descriptions, distribution maps, typifications as well as a key to the Philippine taxa are presented.