Five new α-methylene-γ-lactone-bearing cembranoid diterpenes, sinularolides A−E (1−5), along with 10 known cembranoids, were isolated from the soft coral Sinularia gibberosa. Their structures were determined by extensive spectroscopic (IR, MS, 2D NMR) data analysis. Compounds 2−5 showed moderate activity against selected tumor cell lines.

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doi.org/10.1021/np040197z
Journal of Natural Products
Staff publications

Li, Guoqiang, Zhang, Yanling, Deng, Zhiwei, van Ofwegen, L., Proksch, Peter, & Lin, Wenhan. (2005). Cytotoxic cembranoid diterpenes from a soft coral Sinularia gibberosa. Journal of Natural Products, 68(5), 649–652. doi:10.1021/np040197z