Chromosomal inversions have been found to be important for adaptation. These structural variants suppress recombination, allowing groups of variants to be transmitted together. Blumer et al. sequenced 1375 genomes from 240 species of Lake Malawi cichlids, a clade of fish hallmarked by their extremely species-rich adaptive radiations in several African lakes. The authors found multiple segregating inversions in these populations, as well as genomic signatures showing that these regions had been used repeatedly in adaptation throughout these species. Some of these inversions seem to primarily include genes related to sensory tissues, and two were linked to sex determination. — Corinne Simonti

doi.org/10.1126/science.adr9961
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Blumer, L.M., Burskaia, V., Artiushin, I., Svardal, H., & [et al.]. (2025). Introgression dynamics of sex-linked chromosomal inversions shape the Malawi cichlid radiation. Science, 388(6752). doi:10.1126/science.adr9961