Six species of Amanita (Amanitaceae, Basidiomycota, Fungi), collected in the Pakaraima Mountains of Guyana, are described; four as new and two as new records for Guyana: A. aurantiobrunnea spec, nov., A. calochroa spec, nov., A. cyanopus spec. nov., A. perphaea spec. nov., A. lanivolva Bas, and A. xerocybe Bas. All six species have been collected in forests dominated by Dicymbe (Caesalpiniaceae) and are assumed to be ectomycorrhizal. Amanita perphaea is commonly eaten by Patamona Indians and is called ‘Pulutukwe’.