2016-03-01
Carteritins A and B, cyclic heptapeptides from the marine sponge Stylissa carteri
Publication
Publication
Tetrahedron Letters , Volume 57 - Issue 11 p. 1285- 1288
Two new cyclic heptapeptides, carteritins A and B (1 and 2), were isolated from the marine sponge Stylissa carteri along with three known cyclic heptapeptides, phakellistatin 13 (3) and hymenamides C and D (4 and 5). Their structures were elucidated based on data obtained using 2D NMR, HRESIMS, and ESIMS/MS, in addition to Marfey’s analysis. Carteritin A (1) showed cytotoxicities against HeLa, HCT116, and RAW264 cells with IC50 values of 0.70–1.5 μM.
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| doi.org/10.1016/j.tetlet.2016.02.031 | |
| Tetrahedron Letters | |
| Organisation | Staff publications |
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Afifi, Ahmed H., El-Desoky, Ahmed H., Kato, Hikaru, Mangindaan, Remy E.P., de Voogd, N., Ammar, Nagwa M., Hifnawy, Mohammed S.& Tsukamoto, Sachiko. (2016). Carteritins A and B, cyclic heptapeptides from the marine sponge Stylissa carteri. Tetrahedron Letters, 57(11), 1285–1288.https://doi.org/10.1016/j.tetlet.2016.02.031 |
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